izindaba

I-Splanchnic inversion (okuhlanganisa ingqikithi ye-splanchnic inversion [dextrocardia] kanye nengxenye ye-splanchnic inversion [levocardia]) kuyisimo esingavamile sokuthuthukiswa kokuzalwa lapho isiqondiso sokusatshalaliswa kwe-splanchnic ezigulini siphambene nalokho kwabantu abavamile. Sibone ukwanda okukhulu kwenani lamacala e-fetus visceral inversion aqinisekiswe yi-ultrasound esibhedlela sethu ezinyangeni ezimbalwa ngemuva kokukhanselwa kwenqubomgomo "yokungabi nalutho" ye-COVID-19 e-China.

Ngokubuyekeza idatha yomtholampilo evela ezikhungweni zokubelethisa ezimbili ezifundeni ezihlukene zase-China, sinqume isigameko sokuguquguquka kwe-visceral yengane kusukela ngoJanuwari 2014 kuya kuJulayi 2023. Ezinyangeni eziyisikhombisa zokuqala zika-2023, isigameko sokuguquguquka kwangaphakathi (i-ultrasonography evamile yangaphambi kokubeletha kanye nokuxilongwa cishe eminyakeni engu-20 kuya kwengu-24 ubudala ngaphandle kokuqeqeshwa okungaphezulu kodokotela ngaphandle koshintsho lwe-gesta) izikhathi eziphakeme kunesilinganiso sezehlakalo zonyaka ka-2014-2022 kuzo zombili izikhungo (Umfanekiso 1).

Isigameko sokushintshwa kwe-visceral safinyelela umvuthwandaba ngo-Ephreli 2023 futhi sahlala siphezulu kwaze kwaba nguJuni 2023. Kusukela ngoJanuwari 2023 kuya kuJulayi 2023, kwatholakala izehlakalo ezingama-56 ze-splanchnosis (ingqikithi engu-52 ye-splanchnosis kanye ne-4 ingxenye ye-splanchnosis). Isibalo sokutheleleka kwe-SARS-CoV-2 senyuke ngemuva kokukhanselwa kwenqubomgomo ye-COVID-19 “zero clearance”, okulandelwa ukwanda kwamacala okuguqulwa kwe-visceral. Kulinganiselwa ukuthi ukwanda kwezifo ze-SARS-CoV-2 kwaqala ekuqaleni kukaDisemba 2022, kwafinyelela inani eliphakeme cishe ngoDisemba 20, 2022, futhi kwaphela ekuqaleni kukaFebhuwari 2023, kwagcina kuthinte cishe ama-82% abantu baseChina. Nakuba zingekho iziphetho ezingafinyelelwa mayelana nembangela, esikubonile kuphakamisa ukuhlobana okungenzeka phakathi kokutheleleka kwe-SARS-CoV-2 kanye nokuguqulwa kwe-fetus visceral, okugunyaza ukuqhubeka.funda.

Umfanekiso A ubonisa izehlakalo eziqinisekisiwe zokuguquguquka kwe-fetus splanchnic ezikhungweni ezimbili zokubelethisa kusukela ngoJanuwari 2014 kuya kuJulayi 2023. Amanani aphezulu eshadi lebha abonisa isamba senani lezigameko zonyaka ngamunye. Izehlakalo zibikwe njengenani lamacala kwabesifazane abakhulelwe abayi-10,000 abahlolwa nge-ultrasound. Umfanekiso B ubonisa inani lamacala aqinisekisiwe okuguqulwa kwe-visceral kusukela ngoJanuwari 2023 kuya kuJulayi 2023 e-China Welfare Society International Peace Maternal and Child Health Hospital (IPMCH) e-Shanghai kanye ne-Hunan Provincial Maternal and Child Health Hospital (HPM) e-Changsha.

I-Congenital visceral inversion ihlotshaniswa nokusatshalaliswa kwehomoni ye-morphogenetic okungavamile kanye nokungasebenzi kahle kwe-cilium yesihleli esingakwesokunxele esigabeni sokuqala sokukhulelwa se-embryo kwesokunxele ne-asymmetry ye-eksisi yesokudla. Yize ukudluliswa okuqondile kwe-SARS-CoV-2 kusenempikiswano, ukutheleleka kombungu ekukhulelweni kusencane kungase kuthinte ukukhula kwe-fetus visceral asymmetrical. Ngaphezu kwalokho, i-SARS-CoV-2 ingase ithinte ngokungaqondile ukusebenza kwesikhungo sezicubu ezingakwesokunxele kwesokudla ngokusebenzisa impendulo yayo yokuvuvukala komama, ngaleyo ndlela iphazamise ukukhula kwe-visceral asymmetrical. Ezifundweni ezizayo, ukuhlaziya okwengeziwe kuyadingeka ukuze kuqinisekiswe ukuthi ukungahambi kahle kwezakhi zofuzo okuhlobene ne-primary ciliary dyskinesia okungenzeka ukuthi akuzange kubonwe ekuhlolweni kofuzo ngaphambi kokubeletha akunacala kulawa macala, kanye nokuhlola indima engaba khona yezici zemvelo ekwandeni kwe-visceral inpositions. Kufanele kuqashelwe ukuthi yize izehlakalo zokuguquguquka kwe-visceral zenyuka ezikhungweni zokubelethisa ezimbili ngemuva kokuhlinzwa kokutheleleka kwe-SARS-CoV-2, isimo somtholampilo sokuguquguquka kwe-visceral siseyivelakancane kakhulu.